Zinc & Aging part II Genetic Data

[samanthagonzales]

Here are the representative networks for mouse, human, and rat data. I've also included a zip folder containing everything needed to recreate them.
I couldn't get the human network to be similar in size to the others (the Markov blanket for fasting alone is 48 nodes).
I'm also happy to help annotate them once you've looked over and confirmed if these are what you were looking for.

Update: fixed a naming convention issue in the human network that was preventing the GeNIe file from opening properly. Mouse network was missing the fasting node.

[samanthagonzales]

Here are the results from CalcProb, filtered for p-values > .995 and < .005.

Let me know if you have any questions!

[samanthagonzales]

Here are the results from generating a consensus causal graph using the workflow posted in https://github.com/smlgfiuedu/zn-aging-consensus-graphs -
Let me know if you have any questions!

Human:

human_consensus.graph.pdf

(61.89 KiB) Downloaded 525 times

human_representative_consensus.xlsx

(110.31 KiB) Downloaded 557 times

human_representative_consensus_scores.xlsx

(2.74 MiB) Downloaded 641 times

Mouse:

mouse_consensus.graph.pdf

(46.38 KiB) Downloaded 486 times

mouse_representative_consensus.xlsx

(43.33 KiB) Downloaded 478 times

mouse_representative_consensus_scores.xlsx

(1.22 MiB) Downloaded 587 times

Rat:

rat_consensus.graph.pdf

(52.2 KiB) Downloaded 500 times

rat_representative_consensus.xlsx

(46.13 KiB) Downloaded 486 times

rat_representative_consensus_scores.xlsx

(495.16 KiB) Downloaded 551 times