Zinc & Aging part II Genetic Data

Re: Zinc & Aging part II Genetic Data

Postby rpazo001 » Thu May 18, 2023 5:18 pm

I rework Zhenghua's script so that each BDE score can be analyzed. I also left the values in the negative format. BDE score 7 and 8 are the best network .

##### Rework
> bde=vector()
> bde[1] = -3792.715
> bde[2] = -3681.208
> bde[3] = -3630.236
> bde[4] = -3627.093
> bde[5] = -3615.076
> bde[6]= -3627.093
> bde[7] = -3603.086
> bde[8]= -3603.086
> bde[9]= -3621.687
>
> per1 =vector()
> for(i in 1:9){
+ per1[i] = exp(-log(sum(exp(bde-bde[i]))))
+ }
>
> per1
[1] 2.208718e-83 5.902217e-35 8.088602e-13 1.874395e-11
[5] 3.102972e-06 1.874395e-11 4.999984e-01 4.999984e-01
[9] 4.175005e-09
rpazo001
 
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Re: Zinc & Aging part II Genetic Data

Postby rpazo001 » Fri Jun 02, 2023 2:45 pm

> ##### Rework
> bde=vector()
> bde[1] = -3792.715 ###1000 restarts
> bde[2] = -3681.208 ###5000 restarts
> bde[3] = -3630.236 ###10000 restarts
> bde[4] = -3627.093 ###20000 restarts
> bde[5] = -3615.076 ###20000 restarts
> bde[6]= -3627.093 ###20000 restarts
> bde[7] = -3603.086 ###40000 restarts using best DAG from 20000
> bde[8]= -3603.086 ###40000 restarts using best DAG from 20000
> bde[9]= -3621.687 ###40000 restarts random DAG
> bde[10]= -3598.474 ####80000 restarts using best DAG from 40000
> bde[11]= -3596.369 ####80000 restarts using best DAG from 40000
> bde[12]= -3596.341 ###160000 restarts using best DAG from 40000
>
>
>
> per1 =vector()
> for(i in 1:12){
+ per1[i] = exp(-log(sum(exp(bde-bde[i]))))
+ }
>
>
> per1
[1] 2.483361e-86 6.636127e-38 9.094378e-16 2.107466e-14
[5] 3.488810e-09 2.107466e-14 5.621707e-04 5.621707e-04
[9] 4.694145e-12 5.660233e-02 4.645412e-01 4.777321e-01
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Re: Zinc & Aging part II Genetic Data

Postby rpazo001 » Sat Jun 03, 2023 11:48 am

Pearson Correlation's
Attachments
Pearson Correlations.docx
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Re: Zinc & Aging part II Genetic Data

Postby rpazo001 » Wed Jul 05, 2023 1:38 pm

Mouse dataset
Attachments
Mousedata.csv
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Re: Zinc & Aging part II Genetic Data

Postby rpazo001 » Sun Jul 16, 2023 2:30 pm

Mouse network dot file
Mouse netfile
Attachments
MouseBNtext.txt
netfile
(1.76 MiB) Downloaded 21 times
dagmouse.dot
(409.86 KiB) Downloaded 20 times
Last edited by rpazo001 on Thu Jul 27, 2023 11:22 am, edited 1 time in total.
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Re: Zinc & Aging part II Genetic Data

Postby rpazo001 » Sun Jul 16, 2023 2:49 pm

Human network dot file, netfile, data
Attachments
Humandata.csv
human data
(103.66 KiB) Downloaded 19 times
HumanBNtext.txt
net file
(136.65 KiB) Downloaded 23 times
daghuman.dot
dotfile
(66.04 KiB) Downloaded 19 times
Last edited by rpazo001 on Thu Jul 27, 2023 11:17 am, edited 2 times in total.
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Re: Zinc & Aging part II Genetic Data

Postby rpazo001 » Sun Jul 16, 2023 3:04 pm

Rat network dot file
Rat network net file ( I had to save it as a text file to post)
Data for network
Attachments
BNRAT textfile.txt
net file
(466.4 KiB) Downloaded 26 times
RATBNZ.csv
data
(16.54 KiB) Downloaded 22 times
dagrat.dot
dot file
(31.8 KiB) Downloaded 22 times
Last edited by rpazo001 on Thu Jul 27, 2023 8:14 am, edited 1 time in total.
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Re: Zinc & Aging part II Genetic Data

Postby rpazo001 » Thu Jul 20, 2023 2:24 pm

Data for BANJO
Attachments
BANJO12.csv
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Re: Zinc & Aging part II Genetic Data

Postby samanthagonzales » Wed Aug 02, 2023 2:49 pm

Here are the unformatted networks for 3 independent 1-hour banjo runs on the BANJO12 data (552 mouse genes+fasting).
Fasting is highlighted in yellow - ctrl-F to find the node does not work in Firefox, but works in Edge and Chrome.
Attachments
mouse500.r1.fasting.svg
(1.59 MiB) Downloaded 20 times
mouse500.r2.fasting.svg
(1.7 MiB) Downloaded 16 times
mouse500.r3.fasting.svg
(1.62 MiB) Downloaded 21 times
mouse500_dot_files.zip
dot graphs to generate figures
(35.57 KiB) Downloaded 21 times
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Re: Zinc & Aging part II Genetic Data

Postby samanthagonzales » Tue Aug 29, 2023 10:48 am

The mouse representative network (roughly 30 genes) -
I used the genes from (1) the MB of fasting, (2) the genes of interest (3) top 10 genes with highest probabilities 'finalmouseprobs8_8' and (4) the MB of the top 10 genes.
Attachments
mouse_representative_network.png
image file for mouse representative network
mouse_representative_network.png (278.46 KiB) Viewed 368 times
mouse_goi_bayes_fitted_iss=1.net
.net file for mouse representative network
(15.9 KiB) Downloaded 17 times
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