Zinc & Aging part II Genetic Data

Re: Zinc & Aging part II Genetic Data

Postby samanthagonzales » Wed Aug 30, 2023 12:42 pm

Here are the representative networks for mouse, human, and rat data. I've also included a zip folder containing everything needed to recreate them.
I couldn't get the human network to be similar in size to the others (the Markov blanket for fasting alone is 48 nodes).
I'm also happy to help annotate them once you've looked over and confirmed if these are what you were looking for. :D

Update: fixed a naming convention issue in the human network that was preventing the GeNIe file from opening properly. Mouse network was missing the fasting node.
Attachments
mouse_representative_network.png
mouse network - 29 genes
mouse_representative_network.png (283.81 KiB) Viewed 1149 times
human_representative_network.png
updated naming conventions for genie
human_representative_network.png (337.46 KiB) Viewed 1152 times
zinc and aging.zip
updated R environment/files
(154.98 MiB) Downloaded 44 times
rat_representative_network.png
rat network - 31 genes
rat_representative_network.png (172.44 KiB) Viewed 1155 times
samanthagonzales
 
Posts: 42
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Re: Zinc & Aging part II Genetic Data

Postby samanthagonzales » Wed Oct 25, 2023 12:08 pm

Here are the results from CalcProb, filtered for p-values > .995 and < .005.

Let me know if you have any questions!
Attachments
calcprob.zn.aging.human.filtered995-005.results.txt.tar.gz
(70.46 MiB) Downloaded 46 times
calcprob.zn.aging.mouse.filtered995-05.results.txt.tar.gz
(294.64 MiB) Downloaded 51 times
calcprob.zn.aging.rat.intake.filtered995-005.results.txt.tar.gz
(164.16 MiB) Downloaded 50 times
rat.zinc.results.calcprob.2023.09.19-14.42.txt
(459.05 KiB) Downloaded 47 times
samanthagonzales
 
Posts: 42
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Re: Zinc & Aging part II Genetic Data

Postby samanthagonzales » Tue Dec 19, 2023 12:41 pm

Here are the results from generating a consensus causal graph using the workflow posted in https://github.com/smlgfiuedu/zn-aging-consensus-graphs -
Let me know if you have any questions!

Human:
human_consensus.graph.pdf
(61.89 KiB) Downloaded 48 times

human_representative_consensus.xlsx
(110.31 KiB) Downloaded 49 times

human_representative_consensus_scores.xlsx
(2.74 MiB) Downloaded 54 times


Mouse:
mouse_consensus.graph.pdf
(46.38 KiB) Downloaded 51 times

mouse_representative_consensus.xlsx
(43.33 KiB) Downloaded 32 times

mouse_representative_consensus_scores.xlsx
(1.22 MiB) Downloaded 43 times


Rat:
rat_consensus.graph.pdf
(52.2 KiB) Downloaded 46 times

rat_representative_consensus.xlsx
(46.13 KiB) Downloaded 36 times

rat_representative_consensus_scores.xlsx
(495.16 KiB) Downloaded 50 times
samanthagonzales
 
Posts: 42
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